An update on necrotizing enterocolitis: pathogenesis and preventive strategies
نویسندگان
چکیده
منابع مشابه
An update on necrotizing enterocolitis: pathogenesis and preventive strategies
Necrotizing enterocolitis (NEC) is one of the most critical morbidities in preterm infants. The incidence of NEC is 7% in very-low-birth-weight infants, and its mortality is 15 to 30%. Infants who survive NEC have various complications, such as nosocomial infection, malnutrition, growth failure, bronchopulmonary dysplasia, retinopathy of prematurity, and neurodevelopmental delays. The most impo...
متن کاملUpdate in Pathogenesis and Prospective in Treatment of Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) is among the most common and devastating diseases in neonates and, despite the significant advances in neonatal clinical and basic science investigations, its etiology is largely understood, specific treatment strategies are lacking, and morbidity and mortality remain high. Improvements in the understanding of pathogenesis of NEC may have therapeutic consequences...
متن کاملNecrotizing enterocolitis in newborns: update in pathophysiology and newly emerging therapeutic strategies
While the survival of extremely premature infants with respiratory distress syndrome has increased due to advanced respiratory care in recent years, necrotizing enterocolitis (NEC) remains the leading cause of neonatal mortality and morbidity. NEC is more prevalent in lower gestational age and lower birth weight groups. It is characterized by various degrees of mucosal or transmural necrosis of...
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Necrotizing enterocolitis is the most frequently occurring gastrointestinal disorder in premature neonates. Animal models of necrotizing enterocolitis and prenatal administration of cortisone have demonstrated that cortisone may accelerate maturation of the mucosal barrier, therefore reducing the incidence of this gastrointestinal disorder. The authors present a review of the literature of the ...
متن کاملNecrotizing enterocolitis report of 20 cases
Necrotizing enterocolitis is a disease of unknown origin. Epidemiological observations emphasize the potential roles of infection, enteric feeding and local vascular compromise of the Gastrointestinal tract in the pathogenesis of this disease. Clinical findings include signs of sepsis , plus abdominal distention , vomiting, bloody stool and occasionally , signs of intestinal perforation and pe...
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ژورنال
عنوان ژورنال: Korean Journal of Pediatrics
سال: 2011
ISSN: 1738-1061,2092-7258
DOI: 10.3345/kjp.2011.54.9.368